SCHEMBL11405642

SCHEMBL11405642

C1COC(C2CNCCO2)CN1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.34
DRD3 P35462 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
CYP2C9 P11712 1/20 0.33
SLC6A2 P23975 10/20 0.33
SLC6A4 P31645 10/20 0.33
SLC6A3 Q01959 6/20 0.33
HTR1A P08908 2/20 0.32
ADRB2 P07550 1/20 0.31
HTR2A P28223 1/20 0.31
ADRA1A P35348 1/20 0.31
HTR2B P41595 1/20 0.31
CYP2D6 P10635 1/20 0.31
KCNH2 Q12809 1/20 0.31
ADRA2C P18825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25176293 0.92 DRD2 (0.32) DRD2DRD3SLC6A2SLC6A4SLC6A3
SCHEMBL16878781 0.89 DRD2 (0.31) DRD2DRD3
SCHEMBL16877514 0.89
SCHEMBL28741732 0.85 CHRM2 (0.34)
SCHEMBL17479092 0.84 CCR5 (0.38) DRD2DRD3
SCHEMBL22652946 0.84
SCHEMBL28175046 0.84 DRD2 (0.31) DRD2DRD3
SCHEMBL23745320 0.84
SCHEMBL16877913 0.84 CCR5 (0.38) DRD2DRD3
SCHEMBL516829 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3660069-B1 FAST CURING EPOXY SYSTEMS EVONIK OPERATIONS GMBH (DE) 2024-01-03 EP claimed
EP-3569630-B1 FAST CURING EPOXY SYSTEMS EVONIK OPERATIONS GMBH (DE) 2022-08-03 EP claimed
EP-3569629-B1 FAST CURING EPOXY SYSTEMS EVONIK OPERATIONS GMBH (DE) 2022-07-06 EP claimed
EP-2780384-B2 IMPROVED POLYURETHANE FOAM COMPOSITION SOUDAL (BE) 2020-06-10 EP claimed
CN-111234182-A Fast curing epoxy system 赢创运营有限公司 2020-06-05 CN claimed
US-20200172723-A1 FAST-CURING EPOXY SYSTEMS EVONIK OPERATIONS GMBH (DE) 2020-06-04 US claimed
US-20190352452-A1 FAST-CURING EPOXY SYSTEMS EVONIK DEGUSSA GMBH (DE) 2019-11-21 US claimed
US-20190352449-A1 FAST-CURING EPOXY SYSTEMS EVONIK DEGUSSA GMBH (DE) 2019-11-21 US claimed
CN-107438650-A The sealant and the method for curing by Photolatent catalysts of matrix polymer/epoxide based on sulfydryl end-blocking 凯密特尔有限责任公司 2017-12-05 CN claimed
EP-2780384-B1 IMPROVED POLYURETHANE FOAM COMPOSITION SOUDAL (BE) 2017-08-02 EP claimed
CN-1656073-A Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases NOVARTIS AG (CH) 2005-08-17 CN claimed
EP-3660069-B1 FAST CURING EPOXY SYSTEMS EVONIK OPERATIONS GMBH (DE) 2024-01-03 EP disclosed
WO-2023141825-A1 APPLICATION OF TUNG OIL IN POLYURETHANE COMPOSITION SIKA技术股份公司 2023-08-03 WO disclosed
US-11524966-B1 Carboxamides as ubiquitin-specific protease inhibitors VALO HEALTH, INC. (US) 2022-12-13 US disclosed
EP-3569630-B1 FAST CURING EPOXY SYSTEMS EVONIK OPERATIONS GMBH (DE) 2022-08-03 EP disclosed
CN-107108829-A The reduction of aldehyde in amine catalyst 亨斯迈石油化学有限责任公司 2017-08-29 CN disclosed
CN-107001878-A It is used as adhesion promoter or the silicol of crosslinking agent SIKA技术股份公司 2017-08-01 CN disclosed
CN-106232668-A There is low monomeric diisocyanate content and the polyurethane-hot melt adhesive of good crosslinking rate SIKA技术股份公司 2016-12-14 CN disclosed
US-20150259582-A1 POLYOL COMPOSITIONS FOR HOT MELT ADHESIVES IFS Industries Inc. 2015-09-17 US disclosed
US-4299957-A REACTING N-(2-HYDROXYETHYL)MORPHOLINE WITH EXCESS OF METHANOL IN PRESENCE OF A SILICA-ALUMINUM CATALYST TEXACO INC. (US) 1981-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11524966-B1 Carboxamides as ubiquitin-specific protease inhibitors USP28, USP25, USP24 DRD2 4467/4885DRD3 4307/4885MEN1 3554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.