Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 4/20 | 0.48 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415802 | 0.95 | NFKBIA (0.52) | IDH1NFKBIARELASMN1; SMN2MEN1 | |
| SCHEMBL11405692 | 0.90 | IDH1 (0.42) | IDH1NFKBIARELASMN1; SMN2MEN1 | |
| SCHEMBL11437296 | 0.89 | MEN1 (0.50) | IDH1NFKBIARELASMN1; SMN2MEN1 | |
| SCHEMBL11415799 | 0.87 | NHERF1 (0.46) | IDH1NFKBIARELASMN1; SMN2MEN1 | |
| SCHEMBL11402862 | 0.84 | ALDH1A1 (0.43) | IDH1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL11431457 | 0.84 | IDH1 (0.55) | IDH1 | |
| SCHEMBL11437291 | 0.82 | MAPT (0.44) | IDH1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL11432314 | 0.81 | SMN1; SMN2 (0.51) | IDH1NFKBIARELASMN1; SMN2MEN1 | |
| SCHEMBL11415386 | 0.81 | NFKBIA (0.48) | IDH1NFKBIARELASMN1; SMN2MEN1 | |
| SCHEMBL11466450 | 0.80 | DDX3X (0.52) | NFKBIARELAMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4231958-A | AMINOPHENYLENECARBONYL /AND SULFONYL/IMINONAPHTHALENE INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1980-11-04 | — | — | US | disclosed |
| US-4229370-A | INHIBITORS OF THE COMPLEMENT SYSTEM, IMMUNOLOGY | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4155930-A | Ureylene phenylene anionic naphthalenesulfonic acids | AMERICAN CYANAMID COMPANY (US) | 1979-05-22 | — | — | US | disclosed |