Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5503771 | 0.88 | KMT2A (0.52) | KMT2AALDH1A1SMN1; SMN2BCL2L1MCL1 | |
| SCHEMBL5510059 | 0.88 | KMT2A (0.52) | KMT2AALDH1A1SMN1; SMN2BCL2L1MCL1 | |
| SCHEMBL11344140 | 0.85 | ALDH1A1 (0.48) | KMT2AALDH1A1SMN1; SMN2TDP1POLB | |
| SCHEMBL11422126 | 0.85 | ALDH1A1 (0.48) | KMT2AALDH1A1SMN1; SMN2TDP1POLB | |
| SCHEMBL11344914 | 0.84 | ALDH1A1 (0.48) | KMT2AALDH1A1SMN1; SMN2TDP1POLB | |
| SCHEMBL11528664 | 0.84 | KMT2A (0.51) | KMT2AALDH1A1SMN1; SMN2BCL2L1MCL1 | |
| SCHEMBL11357868 | 0.81 | GSTO1 (0.43) | KMT2AALDH1A1SMN1; SMN2TDP1POLB | |
| SCHEMBL11343142 | 0.81 | GSTO1 (0.53) | KMT2AALDH1A1SMN1; SMN2TDP1POLB | |
| SCHEMBL11348810 | 0.80 | GSTO1 (0.44) | KMT2AALDH1A1SMN1; SMN2TDP1POLB | |
| SCHEMBL11350317 | 0.80 | LMNA (0.57) | KMT2AALDH1A1SMN1; SMN2TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235918-A | SALIDIURETICS, TREATMENT OF HYPERTONIC CONDITIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |