Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404915 | 0.85 | KDM4E (0.30) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL11358553 | 0.84 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL11354328 | 0.83 | TSHR (0.33) | KDM4EALDH1A1TSHRTHRB | |
| SCHEMBL11355868 | 0.82 | THRB (0.33) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL11411040 | 0.82 | THRB (0.33) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL15012822 | 0.79 | TSHR (0.34) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL11354775 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL11406929 | 0.75 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL19122375 | 0.74 | ALDH1A1 (0.38) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL6981102 | 0.73 | BPTF (0.36) | KDM4EALDH1A1GLAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4189610-A | Preparation of 4,4-dioxy-substituted stilbenes | MONSANTO COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0001910-A1 | Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |