Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11355693 | 0.87 | IMPDH2 (0.35) | — | |
| SCHEMBL11355764 | 0.83 | THRB (0.35) | TSHRTHRBALDH1A1KDM4E | |
| SCHEMBL11358205 | 0.83 | THRB (0.35) | TSHRTHRBALDH1A1KDM4E | |
| SCHEMBL11410906 | 0.83 | KDM4E (0.32) | TSHRTHRBALDH1A1KDM4E | |
| SCHEMBL11353888 | 0.77 | THRB (0.34) | TSHRTHRBALDH1A1KDM4E | |
| SCHEMBL11350488 | 0.76 | GABRA1 (0.32) | ALDH1A1KDM4E | |
| SCHEMBL11404915 | 0.75 | KDM4E (0.30) | ALDH1A1KDM4E | |
| SCHEMBL11365947 | 0.72 | L3MBTL1 (0.36) | TSHRALDH1A1KDM4E | |
| SCHEMBL25330005 | 0.72 | ALOX15 (0.37) | TSHRTHRBALDH1A1KDM4E | |
| SCHEMBL11349736 | 0.70 | ALDH1A1 (0.38) | TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001910-B1 | PREPARATION OF 4,4'-DIHYDROXY STILBENES OR DERIVATIVES THEREOF | MONSANTO COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4189610-A | Preparation of 4,4-dioxy-substituted stilbenes | MONSANTO COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0001910-A1 | Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |