Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 6/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11354467 | 0.81 | SCN4A (0.38) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL11410900 | 0.81 | KDM4E (0.36) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL11365754 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SCN4A | |
| SCHEMBL11353888 | 0.79 | THRB (0.34) | KDM4EALDH1A1MAPTTHRBTSHR | |
| SCHEMBL11410906 | 0.78 | KDM4E (0.32) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL9945999 | 0.78 | POLB (0.40) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL11350497 | 0.77 | TAS1R3 (0.42) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL11360731 | 0.77 | RXRA (0.34) | TSHR | |
| SCHEMBL11404915 | 0.74 | KDM4E (0.30) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL9458303 | 0.73 | THRB (0.39) | KDM4EALDH1A1GLAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001910-B1 | PREPARATION OF 4,4'-DIHYDROXY STILBENES OR DERIVATIVES THEREOF | MONSANTO COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4189610-A | Preparation of 4,4-dioxy-substituted stilbenes | MONSANTO COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0001910-A1 | Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |