SCHEMBL11411069

SCHEMBL11411069

CC1N=NC(=O)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 1/20 0.36
ALOX15 P16050 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
GPR3 P46089 2/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
ACHE P22303 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1032657 0.76 KMT2A (0.40) POLBMEN1KMT2AALDH1A1ALOX15
SCHEMBL6314591 0.76 MEN1 (0.40) POLBMEN1KMT2AALDH1A1ALOX15
SCHEMBL9617399 0.76 MEN1 (0.40) POLBMEN1KMT2AALDH1A1ALOX15
SCHEMBL4060635 0.76 MEN1 (0.40) POLBMEN1KMT2AALDH1A1ALOX15
SCHEMBL599351 0.76 S100A4 (0.40) POLBMEN1KMT2AALDH1A1ALOX15
SCHEMBL11052520 0.76 POLB (0.40) POLBMEN1KMT2AALDH1A1ALOX15
SCHEMBL16012917 0.76 MEN1 (0.40) POLBMEN1KMT2AALDH1A1ALOX15
SCHEMBL21533082 0.76 MEN1 (0.36) POLBMEN1KMT2AALDH1A1ALOX15
SCHEMBL10512037 0.76 POLB (0.36) POLBMEN1KMT2AALDH1A1ALOX15
SCHEMBL8011185 0.73 ALDH1A1 (0.46) POLBMEN1KMT2AALDH1A1HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 US claimed
CN-110869359-A Novel compounds and pharmaceutical compositions thereof for the treatment of fibrosis 加拉帕戈斯股份有限公司 2020-03-06 CN disclosed
US-4237215-A DECOMPOSING N-HALO COMPOUND IN PRESENCE OF ORGANIC SILVER SALT TO PRODUCE SILVER HALIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-12-02 US disclosed
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 US disclosed
US-4144072-A CONTAINING A PHTHALAZINONE AND A PHTHALIMIDE FUJI PHOTO FILM CO., LTD. (JP) 1979-03-13 US disclosed
US-4125403-A ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, PHTHALAZINONE, AND A BENZOXAZINEDIONE OR QUINAZOLINEDIONE FUJI PHOTO FILM CO., LTD. 1978-11-14 US disclosed
US-4076534-A Heat developable light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US disclosed