Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CTSC | P53634 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 5/20 | 0.40 |
| ▸ | FAP | Q12884 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369671 | 0.86 | KMT2A (0.50) | DPP4KCNH2GPR6KMT2A | |
| SCHEMBL11378964 | 0.86 | ALDH1A1 (0.48) | RAB9ANPC1DPP4FAPDPP8 | |
| SCHEMBL11378390 | 0.86 | DPP4 (0.41) | CTSBCTSKRAB9ANPC1DPP4 | |
| SCHEMBL11373157 | 0.85 | PREP (0.49) | CTSBCTSKRAB9ANPC1DPP4 | |
| SCHEMBL11372875 | 0.83 | CTSL (0.49) | CTSBCTSKRAB9ANPC1DPP7 | |
| SCHEMBL11376112 | 0.83 | MAPT (0.43) | RAB9ANPC1DPP4KMT2APREP | |
| SCHEMBL11390362 | 0.83 | PREP (0.45) | CTSBCTSKRAB9ANPC1DPP4 | |
| SCHEMBL11380434 | 0.82 | ALOX15 (0.54) | ALOX5RAB9ANPC1DPP4FAP | |
| SCHEMBL11375421 | 0.82 | HDAC1 (0.43) | CTSBCTSSRAB9ANPC1KMT2A | |
| SCHEMBL11368904 | 0.81 | PREP (0.57) | DPP4KMT2APREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282212-A | Immune-stimulating 1-(N-acylcarbamoyl)-2-cyanoaziridines | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-04 | — | — | US | disclosed |