Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381416 | 0.87 | KMT2A (0.44) | ALOX15SMN1; SMN2HTTPOLBNPC1 | |
| SCHEMBL11378964 | 0.85 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1HPGDPOLBNPC1 | |
| SCHEMBL11378390 | 0.85 | DPP4 (0.41) | ALOX15SMN1; SMN2HTTALDH1A1POLB | |
| SCHEMBL11369671 | 0.82 | KMT2A (0.50) | ALOX15SMN1; SMN2ALDH1A1POLBGAA | |
| SCHEMBL11412004 | 0.82 | CTSB (0.47) | ALOX5NPC1RAB9AKMT2ADPP4 | |
| SCHEMBL11387722 | 0.82 | CHRNB2 (0.50) | SMN1; SMN2HTTALDH1A1HPGDPOLB | |
| SCHEMBL11375421 | 0.82 | HDAC1 (0.43) | SMN1; SMN2HTTALDH1A1HPGDPOLB | |
| SCHEMBL11369577 | 0.81 | HTT (0.50) | ALOX15SMN1; SMN2HTTALDH1A1HPGD | |
| SCHEMBL11378167 | 0.81 | DPP4 (0.47) | SMN1; SMN2HTTALDH1A1HPGDCA1 | |
| SCHEMBL11368904 | 0.81 | PREP (0.57) | SMN1; SMN2ALDH1A1HPGDPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282212-A | Immune-stimulating 1-(N-acylcarbamoyl)-2-cyanoaziridines | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-04 | — | — | US | disclosed |