Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954915 | 0.90 | MEN1 (0.46) | TSHRLMNAHTTALDH1A1CYP3A4 | |
| SCHEMBL11501576 | 0.86 | TAAR1 (0.50) | TSHRLMNACHRM2ADRA2AADRA2B | |
| SCHEMBL11315339 | 0.82 | LMNA (0.32) | TSHRLMNAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL11421042 | 0.82 | CRHR1 (0.37) | TSHRLMNACYP1A2CYP2D6KDM4E | |
| SCHEMBL11315356 | 0.82 | TSHR (0.50) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL11694085 | 0.81 | ALDH1A1 (0.41) | LMNAKDM4EALDH1A1CYP3A4MEN1 | |
| SCHEMBL10443160 | 0.81 | TSHR (0.52) | TSHRLMNAHTTALDH1A1MEN1 | |
| SCHEMBL11676094 | 0.80 | LTA4H (0.50) | TSHRCYP1A2CYP2D6HTTKCNH2 | |
| SCHEMBL18562084 | 0.80 | KMT2A (0.37) | TSHRLMNAHTTALDH1A1CYP3A4 | |
| SCHEMBL25399798 | 0.79 | USP2 (0.40) | TSHRLMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233214-A | FOR POLYACRYLONITRILE AND ACID-MODIFIED POLYESTERS OR POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-11 | — | — | US | disclosed |
| US-4036826-A | Cationic azo dyestuffs with a hydroxyalkylated ammonium group | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |