Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.49 |
| ▸ | PDE4A | P27815 | 3/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2952559 | 0.83 | APP (0.55) | TRPM5APPPDE4BPDE4APDE4C | |
| SCHEMBL13001927 | 0.83 | PDE4B (0.52) | TRPM5APPPDE4BPDE4APDE4C | |
| SCHEMBL7002288 | 0.83 | APP (0.55) | TRPM5APPPDE4BPDE4APDE4C | |
| SCHEMBL7002284 | 0.83 | APP (0.55) | TRPM5APPPDE4BPDE4APDE4C | |
| SCHEMBL21024669 | 0.82 | LTB4R (0.57) | TRPM5APPKDM4EALDH1A1LTB4R | |
| SCHEMBL2950480 | 0.78 | LTB4R (0.61) | TRPM5APPKDM4EALDH1A1PDE4D | |
| SCHEMBL15805111 | 0.77 | PDE4B (0.62) | APPKDM4EALDH1A1PDE4BPDE4A | |
| SCHEMBL15799414 | 0.77 | PDE4B (0.62) | APPKDM4EALDH1A1PDE4BPDE4A | |
| SCHEMBL17259138 | 0.77 | PDE4B (0.62) | APPKDM4EALDH1A1PDE4BPDE4A | |
| SCHEMBL6318372 | 0.77 | APP (0.59) | TRPM5APPPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188338-A | ANTICOAGULANTS | AKZONA INCORPORATED (US) | 1980-02-12 | — | — | US | claimed |
| US-4188338-A | ANTICOAGULANTS | AKZONA INCORPORATED (US) | 1980-02-12 | — | — | US | disclosed |
| US-4173652-A | ANTICOAGULANTS | AKZONA INCORPORATED (US) | 1979-11-06 | — | — | US | disclosed |