Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.57 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.56 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950480 | 0.84 | LTB4R (0.61) | LTB4RTRPM5ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11415936 | 0.82 | HDAC4 (0.54) | LTB4RTRPM5ALDH1A1APPKDM4E | |
| SCHEMBL2952559 | 0.81 | APP (0.55) | TRPM5APPKMT2A | |
| SCHEMBL7002288 | 0.81 | APP (0.55) | TRPM5APPKMT2A | |
| SCHEMBL7002284 | 0.81 | APP (0.55) | TRPM5APPKMT2A | |
| SCHEMBL15706299 | 0.79 | DEGS1 (0.82) | DEGS1ALDH1A1NAMPTHTTLMNA | |
| SCHEMBL26373212 | 0.78 | DEGS1 (0.67) | DEGS1ALDH1A1NAMPTHTTLMNA | |
| SCHEMBL13001927 | 0.78 | PDE4B (0.52) | TRPM5APP | |
| SCHEMBL10123277 | 0.77 | DEGS1 (0.70) | DEGS1ALDH1A1NAMPTHTTLMNA | |
| SCHEMBL871979 | 0.77 | DEGS1 (0.70) | DEGS1ALDH1A1NAMPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3485883-A1 | METHODS OF TREATING EYE DISEASES ASSOCIATED WITH INFLAMMATION AND VASCULAR PROLIFERATION | OccuRx Pty Ltd (AU) | 2019-05-22 | — | — | EP | disclosed |