SCHEMBL11416481

SCHEMBL11416481

N#CSCSC(=O)c1ccc(Cl)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
CASP1 P29466 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KDM4E B2RXH2 1/20 0.49
MAPT P10636 1/20 0.49
ALDH1A1 P00352 2/20 0.46
MAPK1 P28482 1/20 0.46
HIF1A Q16665 1/20 0.46
GABRA1 P14867 6/20 0.43
GABRG2 P18507 6/20 0.43
GABRB3 P28472 6/20 0.43
GABRB2 P47870 4/20 0.43
CTSL P07711 1/20 0.43
POLB P06746 2/20 0.43
THRB P10828 1/20 0.43
RECQL P46063 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
GABRB1 P18505 2/20 0.43
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11423319 0.88 ALDH1A1 (0.50) TSHRCASP1SMN1; SMN2KDM4EMAPT
SCHEMBL11415778 0.81 ALDH1A1 (0.47) SMN1; SMN2MAPTALDH1A1POLBHPGD
SCHEMBL21916240 0.79 KDM4E (0.49) TSHRCASP1SMN1; SMN2KDM4EMAPT
SCHEMBL3770989 0.78 ALDH1A1 (0.57) TSHRCASP1SMN1; SMN2KDM4EMAPT
SCHEMBL11416058 0.78 CYP1A2 (0.43) TSHRKDM4EMAPTALDH1A1MAPK1
SCHEMBL11430781 0.73 HPGD (0.38) CASP1KDM4EMAPTALDH1A1L3MBTL1
SCHEMBL11416483 0.72 GABRA1 (0.42) TSHRCASP1SMN1; SMN2KDM4EMAPT
Acetonitrile SCHEMBL28488651 0.70 TSHR (0.78) TSHRCASP1SMN1; SMN2KDM4EMAPT
SCHEMBL10228777 0.70 ALDH1A1 (0.54) TSHRCASP1SMN1; SMN2KDM4EMAPT
SCHEMBL5666673 0.70 TSHR (0.59) TSHRCASP1SMN1; SMN2KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4198428-A PESTICIDES, MICROBIOCIDES, MOLLUSCOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-04-15 US disclosed