Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3761650 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TSHRSMN1; SMN2MAPTKMT2A | |
| SCHEMBL30377988 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TSHRSMN1; SMN2MAPTKMT2A | |
| SCHEMBL11416481 | 0.78 | TSHR (0.50) | ALDH1A1MAPK1HIF1ATSHRCASP1 | |
| SCHEMBL7806257 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MAPK1HIF1ATSHRCASP1 | |
| SCHEMBL954348 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MAPK1HIF1ATSHRCASP1 | |
| SCHEMBL29487646 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MAPK1HIF1ATSHRCASP1 | |
| SCHEMBL6942669 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPK1HIF1ATSHRCASP1 | |
| SCHEMBL1038187 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2AERCC5FEN1 | |
| SCHEMBL3765830 | 0.74 | MAPT (0.52) | ALDH1A1MAPTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL3767429 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTKMT2AERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140194473-A1 | IMIDAZOLE FUNGICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-07-10 | — | — | US | disclosed |
| US-7851473-B2 | Amide compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20080312226-A1 | Amide Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-18 | — | — | US | disclosed |
| EP-1813606-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312226-A1 | Amide Compound | FAAH, FAAH2, CNR2 | ALDH1A1 353/4885MAPK1 2636/4885HIF1A 46/4885 |
| US-20140194473-A1 | IMIDAZOLE FUNGICIDES | CYP1A1, CYP1B1, CYP2E1 | ALDH1A1 407/4885MAPK1 1245/4885HIF1A 3576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.