Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | QDPR | P09417 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6801606 | 0.90 | NOTUM (0.71) | MAPTLMNANOTUMSMN1; SMN2TP53 | |
| SCHEMBL11418702 | 0.85 | MAPT (0.52) | MAPTLMNANOTUMHDAC1HDAC6 | |
| SCHEMBL3174196 | 0.83 | LMNA (0.50) | MAPTLMNANOTUMHDAC1HDAC6 | |
| SCHEMBL9728 | 0.80 | MAPT (1.00) | MAPTLMNANOTUMHDAC1HDAC6 | |
| Sulfuric Acid SCHEMBL11038813 | 0.78 | PTGS2 (0.47) | MAPTLMNAHPGDSMN1; SMN2NPC1 | |
| Dalfampridine SCHEMBL3245918 | 0.78 | TSHR (0.68) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| Methyl Alcohol SCHEMBL28030205 | 0.78 | MAPT (0.79) | MAPTLMNANOTUMHDAC1HDAC6 | |
| SCHEMBL10860810 | 0.78 | MAPT (0.44) | MAPTLMNANOTUMHDAC1HDAC6 | |
| SCHEMBL9120813 | 0.77 | MAPT (0.92) | MAPTLMNANOTUMHDAC1HDAC6 | |
| Hydrogen Sulfide SCHEMBL3929756 | 0.77 | MAPT (0.92) | MAPTLMNANOTUMHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4187076-A | Paraquat detection method | THE UNIVERSITY OF MISSISSIPPI (US) | 1980-02-05 | — | — | US | claimed |
| US-4187076-A | Paraquat detection method | THE UNIVERSITY OF MISSISSIPPI (US) | 1980-02-05 | — | — | US | disclosed |