Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 6/20 | 0.38 |
| ▸ | HTR1D | P28221 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 5/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418721 | 0.89 | HTR1F (0.52) | HTR1FDRD2DRD1CHRM3HTR1B | |
| Hydrochloric Acid SCHEMBL11432883 | 0.88 | HTR1F (0.51) | HTR1FDRD2DRD1CHRM3HTR1B | |
| SCHEMBL7413233 | 0.83 | HTR1F (0.52) | HTR1FHTR1BHTR1DKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7408517 | 0.82 | HTR1F (0.51) | HTR1FHTR1BHTR1DKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7410143 | 0.82 | HTR1F (0.48) | HTR1FDRD2DRD1CHRM3HTR1B | |
| SCHEMBL7404381 | 0.80 | HTR1F (0.50) | HTR1FDRD2DRD1CHRM3HTR1B | |
| SCHEMBL7407128 | 0.79 | HTR1F (0.67) | HTR1FDRD1HTR1BHTR1DKMT2A | |
| SCHEMBL6963427 | 0.79 | HTR1F (0.58) | HTR1FDRD2DRD1CHRM3HTR1B | |
| SCHEMBL7408494 | 0.79 | HTR1F (0.58) | HTR1FDRD1HTR1BHTR1DHTR1A | |
| SCHEMBL7407846 | 0.79 | DRD2 (0.50) | HTR1FDRD2DRD1CHRM3HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224335-A | INOTROPIC AGENTS USED FOR TREATING CONGESTIVE HEART FAILURE IN MAMMALS | STERLING DRUG INC. (US) | 1980-09-23 | — | — | US | claimed |
| US-4224335-A | INOTROPIC AGENTS USED FOR TREATING CONGESTIVE HEART FAILURE IN MAMMALS | STERLING DRUG INC. (US) | 1980-09-23 | — | — | US | disclosed |