Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | BLM | P54132 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MITF | O75030 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636416 | 0.84 | DNM1 (1.00) | DNM1MAPTBLMRAB9AMAPK1 | |
| SCHEMBL19409875 | 0.75 | MAPT (0.61) | DNM1MAPTRAB9AMAPK1TDP1 | |
| SCHEMBL15019989 | 0.75 | DNM1 (0.73) | DNM1MAPTBLMRAB9AMAPK1 | |
| SCHEMBL15020041 | 0.73 | DNM1 (0.69) | DNM1MAPTBLMRAB9AMAPK1 | |
| SCHEMBL15020045 | 0.73 | DNM1 (0.69) | DNM1MAPTBLMRAB9AMAPK1 | |
| SCHEMBL15039495 | 0.73 | DNM1 (0.69) | DNM1MAPTBLMRAB9AMAPK1 | |
| SCHEMBL15039538 | 0.72 | DNM1 (0.61) | DNM1MAPTBLMRAB9AMAPK1 | |
| SCHEMBL30092600 | 0.71 | ERBB2 (0.45) | MAPTBLMMAPK1TDP1KDM4E | |
| SCHEMBL15022768 | 0.71 | DNM1 (0.71) | DNM1MAPTBLMRAB9AMAPK1 | |
| SCHEMBL15019784 | 0.71 | DNM1 (0.59) | DNM1MAPTBLMRAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4222958-A | HAIR DYES | L'OREAL (FR) | 1980-09-16 | — | — | US | disclosed |
| US-4054147-A | 4,4-Disubstituted diphenylamines in dye compositions for keratinic fibers | L'OREAL (FR) | 1977-10-18 | — | — | US | disclosed |
| US-3981678-A | HAIR DYES | L'OREAL (FR) | 1976-09-21 | — | — | US | disclosed |
| US-3960476-A | OXIDATION BASE | GHILARDI GIULIANA | 1976-06-01 | — | — | US | disclosed |