Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.57 |
| ▸ | CDK4 | P11802 | 1/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052681 | 0.80 | CDK4 (0.49) | MAPTRAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL16296903 | 0.80 | MAPT (0.69) | MAPTRAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL19426943 | 0.78 | MAPT (0.47) | MAPTRAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL10880347 | 0.78 | CDK4 (0.50) | MAPTRAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL8369508 | 0.78 | CDK4 (0.60) | MAPTRAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL1459772 | 0.78 | MAPT (1.00) | MAPTRAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL39057 | 0.78 | MAPT (1.00) | MAPTRAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL8368915 | 0.77 | CDK4 (0.65) | MAPTRAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL11419341 | 0.75 | DNM1 (0.71) | MAPTRAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL9650871 | 0.72 | DNM1 (0.63) | MAPTRAB9AKDM4ENPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283366-A1 | Benzoquinone Derivatives For Treatment Of Cancer And Methods Of Making The Benzoquinone Derivatives | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2017-10-05 | — | — | US | claimed |
| US-20170283366-A1 | Benzoquinone Derivatives For Treatment Of Cancer And Methods Of Making The Benzoquinone Derivatives | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2017-10-05 | — | — | US | disclosed |
| US-20170283366-A1 | Benzoquinone Derivatives For Treatment Of Cancer And Methods Of Making The Benzoquinone Derivatives | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283366-A1 | Benzoquinone Derivatives For Treatment Of Cancer And Methods Of Making The Benzoquinone Derivatives | BRCA1, BBOX1, KMO | MAPT 4775/4885RAB9A 2445/4885KDM4E 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.