Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434198 | 0.86 | MEN1 (0.44) | POLBGAALMNAMEN1KMT2A | |
| SCHEMBL11481169 | 0.78 | POLB (0.59) | POLBGAARAB9ALMNAMEN1 | |
| SCHEMBL11434574 | 0.74 | OPRK1 (0.51) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11696347 | 0.72 | POLB (0.68) | POLBGAARAB9ANPC1LMNA | |
| SCHEMBL11431689 | 0.71 | POLB (0.56) | POLBGAARAB9ANPC1LMNA | |
| SCHEMBL11418705 | 0.71 | MEN1 (0.48) | POLBGAALMNAMEN1KMT2A | |
| SCHEMBL12444397 | 0.69 | POLB (1.00) | POLBGAARAB9ALMNAMEN1 | |
| SCHEMBL29879853 | 0.69 | MGLL (0.55) | POLBLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL19949789 | 0.69 | ADRA1D (0.42) | GAALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL18770800 | 0.69 | MGLL (0.55) | POLBLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239684-A | 1,5'-Benzodiazepine-2-ones, pharmaceutical compositions thereof and method of use thereof | KNOLL AG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-RE30293-E | Process for preparing 1,5-benzodiazepine-2-ones | KNOLL A.G. (DE) | 1980-06-03 | — | — | US | disclosed |
| US-4108852-A | Process for preparing 1,5-benzodiazepine-2-ones | KNOLL AG. (DE) | 1978-08-22 | — | — | US | disclosed |