Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9102541 | 0.85 | HTR7 (0.41) | KDM4EALDH1A1BRD4P2RX4SMN1; SMN2 | |
| SCHEMBL19367156 | 0.84 | P2RX4 (0.37) | KDM4EALDH1A1BRD4P2RX4SMN1; SMN2 | |
| SCHEMBL9107608 | 0.81 | TP53 (0.35) | BRD4P2RX4MAPTHRH4MEN1 | |
| SCHEMBL9102663 | 0.81 | TP53 (0.36) | ALDH1A1BRD4P2RX4SMN1; SMN2MAPT | |
| SCHEMBL9102919 | 0.74 | MAOA (0.53) | ALDH1A1SMN1; SMN2MAPTHPGDALOX15 | |
| SCHEMBL11420554 | 0.73 | KDM4E (0.43) | KDM4EALDH1A1P2RX4SMN1; SMN2HPGD | |
| SCHEMBL20277216 | 0.73 | P2RX4 (0.36) | KDM4EALDH1A1BRD4P2RX4SMN1; SMN2 | |
| SCHEMBL31067286 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1P2RX4SMN1; SMN2MAPT | |
| SCHEMBL47007 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1P2RX4SMN1; SMN2MAPT | |
| SCHEMBL20277146 | 0.72 | P2RX4 (0.38) | KDM4EALDH1A1BRD4P2RX4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268489-A1 | FLUOROGENIC AND CHROMOGENIC SUBSTRATE | LI-COR, INC. (US) | 2018-01-17 | — | — | EP | disclosed |
| US-9632034-B2 | Fluorogenic and chromogenic substrate | LI-COR, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| WO-2016149127-A1 | FLUOROGENIC AND CHROMOGENIC SUBSTRATE | LI-COR, INC. (US) | 2016-09-22 | — | — | WO | disclosed |
| US-20160266045-A1 | FLUOROGENIC AND CHROMOGENIC SUBSTRATE | LI-COR, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |