SCHEMBL114229

SCHEMBL114229

CCCCCOCOCC

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.46
THRB P10828 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 1/20 0.46
CES2 O00748 2/20 0.43
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
USP2 O75604 1/20 0.40
CES1 P23141 1/20 0.39
LPAR5 Q9H1C0 1/20 0.37
LPAR1 Q92633 2/20 0.36
LPAR3 Q9UBY5 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27938265 0.97 THRB (0.50) HTTTHRBMEN1KMT2AMAPT
SCHEMBL27951244 0.97 THRB (0.50) HTTTHRBMEN1KMT2AMAPT
SCHEMBL27938501 0.97 THRB (0.50) HTTTHRBMEN1KMT2AMAPT
SCHEMBL13625923 0.97 THRB (0.50) HTTTHRBMEN1KMT2AMAPT
SCHEMBL7547436 0.92
SCHEMBL1835374 0.91 THRB (0.52) HTTTHRBMEN1KMT2AMAPT
SCHEMBL9497468 0.89 TSHR (0.46) HTTTHRBMEN1KMT2AMAPT
SCHEMBL23567250 0.88 THRB (0.56) HTTTHRBMEN1KMT2AMAPT
SCHEMBL15437258 0.88 HTT (0.39) HTTTHRBMEN1KMT2AMAPT
SCHEMBL12614708 0.88 HTT (0.39) HTTTHRBMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2472661-B1 SECONDARY BATTERY NEC ENERGY DEVICES INC (JP) 2019-03-13 EP disclosed
US-20180342769-A1 ELECTROLYTIC SOLUTION, METHOD FOR PREPARING ESTER COMPOUND CONTAINED THEREIN AND LITHIUM SECONDARY CELL NEC CORPORATION (JP) 2018-11-29 US disclosed
US-9932437-B2 Moisture curable silylated polymer compositions containing reactive modifiers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-04-03 US disclosed
US-9714315-B2 Moisture curable silylated polymer compositions containing reactive modifiers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-07-25 US disclosed
EP-3187558-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS Momentive Performance Materials Inc. (US) 2017-07-05 EP disclosed
EP-2472664-B1 SECONDARY BATTERY NEC ENERGY DEVICES INC (JP) 2017-06-21 EP disclosed
US-9666904-B2 Secondary battery NEC CORPORATION (JP) 2017-05-30 US disclosed
US-9627687-B2 Secondary battery NEC ENERGY DEVICES, LTD. (JP) 2017-04-18 US disclosed
EP-2424949-B1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS MOMENTIVE PERFORMANCE MAT INC (US) 2017-03-01 EP disclosed
US-9203107-B2 Secondary battery NEC ENERGY DEVICES, LTD. (JP) 2015-12-01 US disclosed
US-8809479-B2 Moisture curable silylated polymer compositions containing reactive modifiers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-08-19 US disclosed
US-20130245194-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-09-19 US disclosed
US-20130122353-A1 SECONDARY BATTERY NEC CORPORATION (JP) 2013-05-16 US disclosed
US-20120183843-A1 SECONDARY BATTERY NEC CORPORATION (JP) 2012-07-19 US disclosed
US-20120183842-A1 SECONDARY BATTERY NEC CORPORATION (JP) 2012-07-19 US disclosed
EP-2472661-A1 SECONDARY BATTERY NEC Energy Devices, Inc. (JP) 2012-07-04 EP disclosed
EP-2472664-A1 SECONDARY BATTERY NEC Energy Devices, Inc. (JP) 2012-07-04 EP disclosed
EP-2424949-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS Momentive Performance Materials Inc. (US) 2012-03-07 EP disclosed
US-20100317796-A1 Moisture Curable Silylated Polymer Compositions Containing Reactive Modifiers MOMENTIVE PERFORMANCE MATERIALS INC. 2010-12-16 US disclosed
WO-2010126937-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-11-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180342769-A1 ELECTROLYTIC SOLUTION, METHOD FOR PREPARING ESTER COMPOUND CONTAINED THEREIN AND LITHIUM SECONDARY CELL CEL, CHERP, LMNA HTT 2722/4885THRB 4177/4885MEN1 1575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.