Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 3/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 2/20 | 0.44 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11425433 | 0.91 | CASP6 (0.62) | CASP6CTDSP1CA12CA1CA2 | |
| SCHEMBL11438818 | 0.87 | HSD17B10 (0.51) | CASP6CTDSP1APEX1NT5ETIMP3 | |
| SCHEMBL11351829 | 0.86 | TIMP3 (0.58) | CASP6CTDSP1CA1CA2APEX1 | |
| SCHEMBL10909096 | 0.86 | TIMP3 (0.50) | CASP6CTDSP1CA12CA1CA2 | |
| SCHEMBL11425755 | 0.85 | MAPT (0.42) | CASP6CTDSP1APEX1TIMP3ALDH1A1 | |
| SCHEMBL11433102 | 0.85 | CASP6 (0.42) | CASP6CTDSP1APEX1TIMP3ALDH1A1 | |
| SCHEMBL11431164 | 0.84 | MAPT (0.56) | CASP6ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11436818 | 0.82 | CASP6 (0.63) | CASP6CTDSP1CA12CA1CA2 | |
| SCHEMBL11425964 | 0.82 | CASP6 (0.60) | CASP6CTDSP1CA12CA1CA2 | |
| SCHEMBL11440941 | 0.82 | CASP6 (0.60) | CASP6CTDSP1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |