Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 3/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 3/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11424860 | 0.91 | CASP6 (0.65) | CASP6CTDSP1CA1CA2CA12 | |
| SCHEMBL11433491 | 0.87 | ALDH1A1 (0.47) | CASP6CTDSP1CA1CA2CA12 | |
| SCHEMBL11338837 | 0.86 | TIMP3 (0.53) | CASP6CTDSP1CA1CA2CA12 | |
| SCHEMBL10909110 | 0.86 | CTDSP1 (0.50) | CASP6CTDSP1CA1CA2CA12 | |
| SCHEMBL11424929 | 0.85 | CASP6 (0.44) | CASP6CTDSP1NT5ENSD2ALDH1A1 | |
| SCHEMBL11425641 | 0.85 | CASP6 (0.44) | CASP6CTDSP1CA1CA2CA9 | |
| SCHEMBL11431481 | 0.84 | RAB9A (0.56) | CASP6CTDSP1CA1CA2CA9 | |
| SCHEMBL11424939 | 0.82 | CASP6 (0.57) | CASP6CTDSP1CA1CA2CA12 | |
| SCHEMBL11434098 | 0.81 | CASP6 (0.72) | CASP6CTDSP1CA1CA2CA12 | |
| SCHEMBL11425964 | 0.80 | CASP6 (0.60) | CASP6CTDSP1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |