Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MPL | P40238 | 2/20 | 0.44 |
| ▸ | CD40 | P25942 | 1/20 | 0.43 |
| ▸ | CD40LG | P29965 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433031 | 0.90 | HDAC1 (0.48) | HDAC1CASP6CTDSP1CD40CD40LG | |
| SCHEMBL11427817 | 0.88 | HSD17B10 (0.50) | HDAC1MPLCYP1A2MAPTCYP2C9 | |
| SCHEMBL11355263 | 0.86 | TIMP3 (0.54) | MPLCD40CD40LGMEN1KMT2A | |
| SCHEMBL11433094 | 0.86 | TTR (0.46) | HDAC1CASP6CTDSP1CD40CD40LG | |
| SCHEMBL10907534 | 0.86 | CD40 (0.50) | MPLCD40CD40LGMEN1KMT2A | |
| SCHEMBL11436209 | 0.84 | MEN1 (0.41) | HDAC1CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL11440925 | 0.84 | MEN1 (0.41) | HDAC1MPLCD40CD40LGCYP1A2 | |
| SCHEMBL11433370 | 0.83 | CD40 (0.64) | CASP6CTDSP1CD40CD40LGMAPT | |
| SCHEMBL11433595 | 0.82 | TRPV1 (0.45) | HDAC1CASP6CTDSP1CD40CD40LG | |
| SCHEMBL11433587 | 0.82 | CASP6 (0.49) | HDAC1CASP6CTDSP1MPLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |