Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | CD40 | P25942 | 2/20 | 0.45 |
| ▸ | CD40LG | P29965 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATIC | P31939 | 1/20 | 0.41 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436219 | 0.88 | HSD17B10 (0.52) | TTRCD40CD40LGCYP1A2HDAC1 | |
| SCHEMBL11798039 | 0.88 | TTR (0.46) | TTRCASP6CTDSP1CD40CD40LG | |
| SCHEMBL11205429 | 0.86 | TIMP3 (0.56) | CD40CD40LGCYP1A2MEN1KMT2A | |
| SCHEMBL10908939 | 0.86 | CD40 (0.52) | TTRCASP6CTDSP1CD40CD40LG | |
| SCHEMBL11427596 | 0.86 | HDAC1 (0.48) | CASP6CTDSP1CD40CD40LGCYP1A2 | |
| SCHEMBL11426641 | 0.85 | CASP6 (0.46) | CASP6CTDSP1CD40CD40LGCYP1A2 | |
| SCHEMBL11438686 | 0.84 | HPSE (0.43) | TTRCD40CD40LGCYP1A2MEN1 | |
| SCHEMBL11425717 | 0.84 | HPSE (0.46) | TTRCD40CD40LGCYP1A2MEN1 | |
| SCHEMBL11423070 | 0.83 | CD40 (0.66) | CASP6CTDSP1CD40CD40LGMEN1 | |
| SCHEMBL11758756 | 0.82 | TIMP3 (0.54) | TTRCASP6CTDSP1CD40CD40LG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |