Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28735911 | 0.79 | TSHR (0.31) | ACHEHSD17B10TSHRKDM4EMEN1 | |
| SCHEMBL15176880 | 0.65 | — | — | |
| SCHEMBL13261866 | 0.63 | CYP3A4 (0.33) | TSHRALDH1A1 | |
| SCHEMBL12281360 | 0.62 | ACHE (0.31) | ACHEHSD17B10TSHRALDH1A1 | |
| SCHEMBL30820071 | 0.60 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL3341503 | 0.60 | L3MBTL1 (0.31) | ALDH1A1KMT2A | |
| SCHEMBL900612 | 0.59 | — | — | |
| SCHEMBL5842041 | 0.58 | — | — | |
| SCHEMBL12165004 | 0.55 | HSD17B10 (0.32) | ACHEHSD17B10TSHRALDH1A1 | |
| SCHEMBL6364093 | 0.54 | ACHE (0.31) | ACHEHSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228103-A | Effecting condensation of nitrohaloarene and formyl derivative of a primary aromatic amine with alkali metal hydroxide | MONSANTO COMPANY (US) | 1980-10-14 | — | — | US | disclosed |
| US-4196146-A | Making nitrodiarylamines from formyl derivatives of aromatic amines and nitrohaloarenes by admixing with certain aqueous salt solutions | MONSANTO COMPANY (US) | 1980-04-01 | — | — | US | disclosed |