Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22323559 | 0.97 | ALDH1A1 (0.44) | ALDH1A1KDM4ENPSR1MEN1KMT2A | |
| SCHEMBL5672034 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4ENPSR1MEN1KMT2A | |
| SCHEMBL21694097 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4ENPSR1MEN1KMT2A | |
| SCHEMBL9342602 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KDM4ENPSR1MEN1KMT2A | |
| SCHEMBL11137750 | 0.85 | ALDH1A1 (0.36) | ALDH1A1KDM4ENPSR1MEN1KMT2A | |
| SCHEMBL17709416 | 0.84 | TSHR (0.36) | ALDH1A1KDM4EGAALMNATSHR | |
| SCHEMBL97771 | 0.82 | THRA (0.40) | KDM4ENPSR1GAAMAPTTHRA | |
| SCHEMBL466235 | 0.82 | THRA (0.40) | KDM4ENPSR1GAAMAPTTHRA | |
| SCHEMBL6905040 | 0.82 | THRA (0.40) | KDM4ENPSR1GAAMAPTTHRA | |
| SCHEMBL1650564 | 0.81 | TDP1 (0.46) | ALDH1A1KDM4ENPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221728-A | CHAIN STOPPED POLYORGANOHYDROGENSILOXANE | GENERAL ELECTRIC COMPANY (US) | 1980-09-09 | — | — | US | disclosed |
| US-4197384-A | Stabilized polycarbonate compositions | GENERAL ELECTRIC COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4138379-A | Organic silane stabilized and plasticized polycarbonate composition | GENERAL ELECTRIC COMPANY (US) | 1979-02-06 | — | — | US | disclosed |