Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.35 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.35 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.35 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.35 |
| ▸ | DDX3X | O00571 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11425022 | 0.92 | KDM4E (0.36) | KDM4EKMT2AMEN1HTTMAPT | |
| SCHEMBL11430473 | 0.86 | KMT2A (0.44) | KDM4EKMT2AMEN1HTTMAPT | |
| SCHEMBL11422158 | 0.84 | KMT2A (0.44) | KDM4EKMT2AMEN1HTTMAPT | |
| SCHEMBL11438814 | 0.84 | MPL (0.46) | KDM4EKMT2AMEN1HTTMAPT | |
| SCHEMBL11428520 | 0.84 | TOP1 (0.42) | KMT2AMEN1HTTMAPTNPC1 | |
| Acetic Acid SCHEMBL11428528 | 0.83 | MPL (0.43) | KDM4EKMT2AMEN1HTTMAPT | |
| SCHEMBL11425015 | 0.82 | TOP1 (0.42) | KMT2AMEN1HTTMAPTNPC1 | |
| SCHEMBL11434112 | 0.81 | TOP1 (0.43) | KMT2AMEN1HTTMAPTMPL | |
| SCHEMBL11438825 | 0.80 | MEN1 (0.41) | KDM4EKMT2AMEN1HTTMAPT | |
| SCHEMBL11426044 | 0.79 | ALDH1A1 (0.46) | KDM4EKMT2AMEN1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |