Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MPL | P40238 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433572 | 0.91 | MPL (0.41) | MEN1KMT2AKDM4EMPLRAB9A | |
| SCHEMBL11438814 | 0.91 | MPL (0.46) | MEN1KMT2AKDM4EMPLRAB9A | |
| SCHEMBL11435261 | 0.89 | AURKA (0.44) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| Acetic Acid SCHEMBL11428528 | 0.88 | MPL (0.43) | MEN1KMT2AKDM4EMPLRAB9A | |
| SCHEMBL11429460 | 0.85 | KMT2A (0.42) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL11422042 | 0.85 | KCNMA1 (0.48) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL11439444 | 0.84 | TTR (0.43) | MEN1KMT2AKDM4EMPLNPC1 | |
| SCHEMBL11432948 | 0.83 | KMT2A (0.40) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL11431132 | 0.83 | KCNMA1 (0.51) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL11438775 | 0.82 | PLG (0.42) | MEN1KMT2ARAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |