Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439949 | 0.91 | CA12 (0.45) | HSD17B10MAPK14CA12CA1CA2 | |
| SCHEMBL11434388 | 0.83 | MAOB (0.44) | CA12CA9ALDH1A1CNR2 | |
| SCHEMBL7719381 | 0.82 | CA12 (0.59) | HSD17B10GPR17CA12CA1CA2 | |
| SCHEMBL30285148 | 0.82 | CA12 (0.59) | HSD17B10GPR17CA12CA1CA2 | |
| SCHEMBL11434522 | 0.79 | CNR2 (0.43) | HPGDALDH1A1CNR2KMT2AL3MBTL1 | |
| SCHEMBL11441207 | 0.79 | LOXL2 (0.43) | HSD17B10ERN1AXLHPGDALDH1A1 | |
| SCHEMBL11426531 | 0.79 | JMJD6 (0.54) | JMJD6PRKDCHPGDALDH1A1TP53 | |
| SCHEMBL11437271 | 0.78 | MAOB (0.43) | HSD17B10CA12CA9HPGDALDH1A1 | |
| SCHEMBL10757017 | 0.77 | TGFBR1 (0.42) | JMJD6CA12CA1CA2CA9 | |
| SCHEMBL11436492 | 0.76 | MAPK14 (0.35) | HSD17B10MAPK14AXLHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |