SCHEMBL11429293

SCHEMBL11429293

Cc1cccc(Oc2c(Cl)cccc2Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.52
ALDH1A1 P00352 2/20 0.52
L3MBTL1 Q9Y468 3/20 0.51
GAA P10253 1/20 0.49
HTT P42858 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
TDP1 Q9NUW8 1/20 0.45
LMNA P02545 3/20 0.44
AR P10275 3/20 0.41
LYN P07948 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 3/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HPGD P15428 1/20 0.41
NPBWR1 P48145 1/20 0.40
MCHR1 Q99705 1/20 0.40
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11431172 0.87 L3MBTL1 (0.47) ACHEALDH1A1L3MBTL1GAAHTT
SCHEMBL9694407 0.81 AR (0.46) ACHEALDH1A1L3MBTL1GAAHTT
SCHEMBL11423612 0.81 ALDH1A1 (0.64) ACHEALDH1A1L3MBTL1GAAHTT
SCHEMBL456868 0.80 ALDH1A1 (0.72) ACHEALDH1A1L3MBTL1GAAHTT
SCHEMBL29398372 0.80 ALDH1A1 (0.72) ACHEALDH1A1L3MBTL1GAAHTT
SCHEMBL29746015 0.80 ALDH1A1 (0.72) ACHEALDH1A1L3MBTL1GAAHTT
SCHEMBL9487087 0.79 ACHE (0.56) ACHEALDH1A1L3MBTL1GAAHTT
SCHEMBL11428693 0.79 TEAD4 (0.45) ACHEALDH1A1L3MBTL1HTTMEN1
SCHEMBL3294402 0.78 ALDH1A1 (0.59) ACHEALDH1A1L3MBTL1GAAHTT
SCHEMBL29377828 0.78 ALDH1A1 (0.69) ACHEALDH1A1L3MBTL1GAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4203145-A Chloro-diphenyl BAYER AKTIENGESELLSCHAFT (DE) 1980-05-13 US disclosed