Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 7/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426202 | 0.88 | RXRA (0.36) | BRD4BCL2MCL1SMN1; SMN2CREBBP | |
| SCHEMBL11426509 | 0.88 | AKR1C3 (0.41) | BRD4HSD17B10SMN1; SMN2CREBBPMAPT | |
| SCHEMBL11441308 | 0.85 | SMN1; SMN2 (0.35) | MAOAMAOBBRD4BCL2MCL1 | |
| SCHEMBL11441378 | 0.82 | BRD4 (0.43) | BRD4HSD17B10SMN1; SMN2CREBBPKDM4E | |
| SCHEMBL11441314 | 0.82 | BRD4 (0.52) | BRD4HSD17B10SMN1; SMN2CREBBPKDM4E | |
| SCHEMBL11551948 | 0.81 | BRD4 (0.40) | MAOAMAOBBRD4HSD17B10SMN1; SMN2 | |
| SCHEMBL11434332 | 0.81 | BRD4 (0.40) | BRD4HSD17B10CREBBP | |
| SCHEMBL11434522 | 0.80 | CNR2 (0.43) | MAOBBRD4SMN1; SMN2CREBBPMAPT | |
| SCHEMBL11428954 | 0.79 | EGFR (0.39) | BRD4KDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11547644 | 0.78 | BRD4 (0.48) | BRD4HSD17B10SMN1; SMN2CREBBPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |