Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441150 | 0.89 | KDM4E (0.43) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11438923 | 0.84 | TAS1R3 (0.37) | TAS1R3TAS1R1TAS1R2MAPTMEN1 | |
| SCHEMBL11442744 | 0.82 | NOX1 (0.42) | TAS1R3TAS1R1TAS1R2MAPTMEN1 | |
| SCHEMBL11442019 | 0.76 | SMN1; SMN2 (0.41) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11434292 | 0.76 | NOX1 (0.40) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11427407 | 0.73 | GAA (0.39) | RAB9ANPC1GAAL3MBTL1 | |
| SCHEMBL11430646 | 0.72 | ITGB3 (0.35) | RAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL11427495 | 0.70 | ALDH1A1 (0.42) | MAPTALDH1A1HSD17B10LMNAGAA | |
| SCHEMBL28310012 | 0.70 | ALDH1A1 (0.44) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11435848 | 0.69 | CXCR5 (0.40) | MAPTALDH1A1KDM4EHPGDCXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228284-A | ANTIINFLAMMATORY AGENTS | Nippon Chemiphar Company, Limited (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4166127-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4101667-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |