Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11430580 | 0.89 | TAS1R3 (0.39) | KDM4EGLAMEN1KMT2AHSD17B10 | |
| SCHEMBL11442019 | 0.87 | SMN1; SMN2 (0.41) | KDM4EMEN1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL11438923 | 0.85 | TAS1R3 (0.37) | KDM4EGLAMEN1KMT2AHSD17B10 | |
| SCHEMBL11427407 | 0.83 | GAA (0.39) | POLBMCL1NPC1RAB9A | |
| SCHEMBL11430646 | 0.82 | ITGB3 (0.35) | POLBMCL1NPC1ALDH1A1RAB9A | |
| SCHEMBL11427495 | 0.82 | ALDH1A1 (0.42) | HSD17B10MAPTALDH1A1LMNA | |
| SCHEMBL11435848 | 0.81 | CXCR5 (0.40) | KDM4ECXCR5FABP4AKR1C3MAPT | |
| SCHEMBL11442744 | 0.80 | NOX1 (0.42) | MEN1KMT2ASMN1; SMN2RYR2TDP1 | |
| SCHEMBL11432336 | 0.80 | TRPA1 (0.41) | KDM4EKMT2ACXCR5SMN1; SMN2AKR1C3 | |
| SCHEMBL11442749 | 0.79 | CXCR5 (0.43) | KDM4EHSD17B10CXCR5FABP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228284-A | ANTIINFLAMMATORY AGENTS | Nippon Chemiphar Company, Limited (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4166127-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4101667-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |