Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PLEC | Q15149 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428444 | 0.87 | NPC1 (0.48) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL11431754 | 0.87 | MAPT (0.40) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL11436996 | 0.87 | KDR (0.46) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL9501879 | 0.85 | NPC1 (0.56) | EGLN1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL11562472 | 0.75 | P2RX1 (0.46) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL13446715 | 0.74 | NQO2 (0.42) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11436009 | 0.73 | NPC1 (0.44) | EGLN1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL13715920 | 0.73 | KDM4E (0.53) | MEN1KMT2AMAPTKDM4EL3MBTL1 | |
| SCHEMBL11429773 | 0.72 | ALDH1A1 (0.58) | HSP90AA1HSP90AB1EGLN1MAPTKDM4E | |
| SCHEMBL11565071 | 0.72 | ALDH1A1 (0.49) | HSP90AB1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4186201-A | ANTIALLERGIC AGENTS | RIKER LABORATORIES, INC. (US) | 1980-01-29 | — | — | US | disclosed |
| US-4147694-A | ANTIALLERGENS, ANTIHISTAMINES | RIKER LABORATORIES, INC. (US) | 1979-04-03 | — | — | US | disclosed |