Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 10/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432085 | 0.92 | MEN1 (0.55) | MAPTRAB9ALMNANPC1MAPK1 | |
| SCHEMBL11433700 | 0.86 | MAPT (0.55) | MAPTRAB9ALMNANPC1MAPK1 | |
| SCHEMBL11428748 | 0.85 | NT5E (0.55) | MAPTRAB9ALMNANPC1MAPK1 | |
| SCHEMBL11421862 | 0.84 | MAPT (0.56) | MAPTRAB9ALMNANPC1MAPK1 | |
| SCHEMBL11434047 | 0.84 | CD40 (0.54) | MAPTRAB9ALMNANPC1MAPK1 | |
| SCHEMBL11432108 | 0.84 | MAPT (0.55) | MAPTRAB9ALMNANPC1MAPK1 | |
| SCHEMBL11435634 | 0.83 | ENPP2 (0.47) | MAPTRAB9ANPC1TDP1MEN1 | |
| SCHEMBL11423192 | 0.82 | SMN1; SMN2 (0.67) | MAPTRAB9ALMNANPC1MEN1 | |
| SCHEMBL11426299 | 0.82 | KCNMA1 (0.45) | MAPTRAB9ALMNANPC1MAPK1 | |
| SCHEMBL11437157 | 0.82 | MEN1 (0.54) | MAPTRAB9ALMNANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |