Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146917 | 0.94 | ACACB (0.50) | QPCTKMT2AMEN1KDM4EATM | |
| SCHEMBL11144615 | 0.82 | TBXAS1 (0.60) | KMT2AMEN1ATMALDH1A1CYP3A4 | |
| SCHEMBL11155584 | 0.81 | HMOX1 (0.64) | QPCTKMT2ALTA4H | |
| SCHEMBL11144638 | 0.80 | IDO1 (0.50) | KMT2AMEN1KDM4ELMNAALDH1A1 | |
| SCHEMBL11382391 | 0.79 | TP53 (0.45) | KDM4EALDH1A1TP53TSHR | |
| SCHEMBL11434313 | 0.79 | LMNA (0.48) | QPCTKMT2AMEN1KDM4EATM | |
| SCHEMBL11145829 | 0.79 | CACNA1B (0.49) | KMT2ALTA4H | |
| SCHEMBL11155406 | 0.78 | TBXAS1 (0.54) | QPCTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL11149487 | 0.78 | CYP19A1 (0.51) | — | |
| Hydrochloric Acid SCHEMBL11147406 | 0.78 | CACNA1B (0.48) | KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009683-A1 | Basic phenyl ethers, pharmaceutical compositions containing them and the preparation of these ethers and compositions | MERCK PATENT GmbH (DE) | 1980-04-16 | — | — | EP | disclosed |