Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428812 | 0.81 | MAPT (0.53) | TSHRRAB9APKMMAPTMEN1 | |
| SCHEMBL11860609 | 0.81 | TSHR (0.75) | TSHRRAB9APKMALDH1A1NPC1 | |
| SCHEMBL11435813 | 0.81 | APEX1 (0.68) | RAB9APKMALDH1A1NPC1HTT | |
| Hydrochloric Acid SCHEMBL11437861 | 0.80 | MAPT (0.52) | TSHRRAB9APKMMAPTMEN1 | |
| Monuron SCHEMBL106717 | 0.79 | TSHR (1.00) | TSHRRAB9APKMALDH1A1NPC1 | |
| Monuron SCHEMBL8539289 | 0.79 | TSHR (1.00) | TSHRRAB9APKMALDH1A1NPC1 | |
| Monuron SCHEMBL9370512 | 0.79 | TSHR (1.00) | TSHRRAB9APKMALDH1A1NPC1 | |
| SCHEMBL197282 | 0.76 | SMN1; SMN2 (0.67) | TSHRRAB9AALDH1A1NPC1HTT | |
| SCHEMBL10613167 | 0.76 | NPC1 (0.83) | TSHRRAB9APKMALDH1A1NPC1 | |
| SCHEMBL11409866 | 0.76 | TSHR (0.72) | TSHRRAB9APKMALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180296505-A1 | BOOSTER DRUG THERAPY FOR MYCOBACTERIUM INFECTIONS | STC UNM (US) | 2018-10-18 | — | — | US | claimed |
| WO-2015126930-A2 | BOOSTER DRUG THERAPY FOR MYCOBACTERIUM INFECTIONS | STC.UNM (US) | 2015-08-27 | — | — | WO | claimed |
| US-4183951-A | PSYCHOTROPIC AGENTS | LABORATOIRE L. LAFON (FR) | 1980-01-15 | — | — | US | claimed |
| US-20180296505-A1 | BOOSTER DRUG THERAPY FOR MYCOBACTERIUM INFECTIONS | STC UNM (US) | 2018-10-18 | — | — | US | disclosed |
| US-20170056345-A1 | BOOSTER DRUG THERAPY FOR MYCOBACTERIUM INFECTIONS | STC.UNM | 2017-03-02 | — | — | US | disclosed |
| WO-2015126930-A2 | BOOSTER DRUG THERAPY FOR MYCOBACTERIUM INFECTIONS | STC.UNM (US) | 2015-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180296505-A1 | BOOSTER DRUG THERAPY FOR MYCOBACTERIUM INFECTIONS | TREH, ACHE, UMPS | TSHR 2580/4885RAB9A 3650/4885PKM 2093/4885 |
| US-20170056345-A1 | BOOSTER DRUG THERAPY FOR MYCOBACTERIUM INFECTIONS | TREH, ACHE, UMPS | TSHR 2580/4885RAB9A 3650/4885PKM 2093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.