Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | MPI | P34949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demannose SCHEMBL1932803 | 1.00 | LMNA (0.41) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Xylose SCHEMBL3862721 | 0.95 | LMNA (0.43) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Sorbitol SCHEMBL247059 | 0.85 | LMNA (0.57) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL11105758 | 0.85 | LMNA (0.57) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Galactose SCHEMBL11013795 | 0.84 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Demannose SCHEMBL1326063 | 0.84 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Demannose SCHEMBL11016379 | 0.84 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Demannose SCHEMBL537703 | 0.83 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Galactose SCHEMBL6900501 | 0.83 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Demannose SCHEMBL329074 | 0.83 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028803-A1 | New penicillanic and cephalosporanic derivatives, preparation thereof and pharmaceutical compositions containing same | Simes S.p.A. (IT) | 1981-05-20 | — | — | EP | claimed |
| EP-0028803-A1 | New penicillanic and cephalosporanic derivatives, preparation thereof and pharmaceutical compositions containing same | Simes S.p.A. (IT) | 1981-05-20 | — | — | EP | disclosed |
| EP-0028803-A1 | New penicillanic and cephalosporanic derivatives, preparation thereof and pharmaceutical compositions containing same | Simes S.p.A. (IT) | 1981-05-20 | — | — | EP | disclosed |