Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533850 | 0.80 | KDM4C (0.38) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL7070074 | 0.80 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10387219 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11420507 | 0.74 | ALDH1A1 (0.78) | ALDH1A1KDM4EMAPTSMN1; SMN2ALKBH5 | |
| SCHEMBL10997289 | 0.73 | POLB (0.47) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL11773330 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9505990 | 0.73 | ALKBH5 (0.66) | ALDH1A1KDM4EMAPTSMN1; SMN2NOTUM | |
| SCHEMBL10995515 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL23398687 | 0.72 | KDM4E (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL7577911 | 0.70 | NOTUM (0.43) | ALDH1A1KDM4EMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4207233-A | Azo dyes containing a thiazole component | BASF AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | disclosed |