Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191420 | 0.81 | KDM4E (0.61) | NOTUMMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7070074 | 0.77 | ALDH1A1 (0.69) | NOTUMMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6763210 | 0.71 | PRKX (0.58) | NOTUMMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL10387219 | 0.70 | ALDH1A1 (0.44) | NOTUMMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11432308 | 0.70 | ALDH1A1 (0.44) | NOTUMMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8663896 | 0.69 | SMN1; SMN2 (0.43) | NOTUMMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL10995515 | 0.67 | ALDH1A1 (0.41) | NOTUMMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11773330 | 0.67 | ALDH1A1 (0.41) | NOTUMMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9505990 | 0.67 | ALKBH5 (0.66) | NOTUMMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11420507 | 0.66 | ALDH1A1 (0.78) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773248-B1 | Polymers with heterocyclic side groups | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-5668245-A | PHENYLENE POLYMERS WITH HETEROCYCLIC SIDE GROUPS | MAXDEM INCORPORATED (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0773248-A1 | Polymers with heterocyclic side groups | MAXDEM INCORPORATED (US) | 1997-05-14 | — | — | EP | disclosed |
| US-4318848-A | Process for the neutralization of basic reaction compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |