Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441467 | 0.87 | MAOB (0.57) | MAOBMAOA | |
| SCHEMBL16740953 | 0.85 | MAOB (0.53) | MAOBBCHE | |
| SCHEMBL11497405 | 0.85 | L3MBTL1 (0.57) | MAOBMAOALTA4HSIGMAR1ALOX5 | |
| SCHEMBL14292431 | 0.83 | SIGMAR1 (0.53) | MAOBMAOASIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL555264 | 0.83 | SIGMAR1 (0.53) | MAOBMAOASIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL11433881 | 0.83 | NPY5R (0.48) | LTA4HPPARGPPARA | |
| SCHEMBL11440388 | 0.81 | MAOB (0.60) | MAOBMAOALTA4HSIGMAR1PPARG | |
| SCHEMBL357349 | 0.81 | MAOB (0.57) | MAOBMAOALTA4HSIGMAR1PPARG | |
| SCHEMBL360368 | 0.81 | MAOB (0.57) | MAOBMAOALTA4HSIGMAR1PPARG | |
| SCHEMBL2736160 | 0.80 | LTA4H (0.61) | MAOBMAOALTA4HSIGMAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009683-A1 | Basic phenyl ethers, pharmaceutical compositions containing them and the preparation of these ethers and compositions | MERCK PATENT GmbH (DE) | 1980-04-16 | — | — | EP | disclosed |