Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | BLK | P51451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435436 | 0.91 | ENPP2 (0.46) | ENPP2CASP6CTDSP1PTGESDEGS1 | |
| SCHEMBL11440357 | 0.87 | ENPP2 (0.51) | ENPP2CASP6CTDSP1DEGS1MAPT | |
| SCHEMBL11337453 | 0.86 | ENPP2 (0.45) | ENPP2PTGESDEGS1MAPTRAB9A | |
| SCHEMBL10907484 | 0.86 | ENPP2 (0.45) | ENPP2CASP6CTDSP1PTGESDEGS1 | |
| SCHEMBL11425014 | 0.85 | CASP6 (0.57) | ENPP2CASP6CTDSP1DEGS1MAPT | |
| SCHEMBL11426058 | 0.83 | CASP6 (0.43) | ENPP2CASP6CTDSP1PTGESMAPT | |
| SCHEMBL11423038 | 0.83 | MEN1 (0.52) | ENPP2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL11433818 | 0.82 | PTGES (0.41) | ENPP2PTGESPLAUNT5E | |
| SCHEMBL11435442 | 0.82 | CASP6 (0.49) | ENPP2CASP6CTDSP1MAPTRAB9A | |
| SCHEMBL11433027 | 0.82 | KAT6A (0.46) | ENPP2CASP6CTDSP1DEGS1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |