Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | BLK | P51451 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441385 | 0.91 | ENPP2 (0.51) | ENPP2CASP6CTDSP1NT5EDEGS1 | |
| SCHEMBL11433813 | 0.87 | ENPP2 (0.46) | ENPP2CASP6CTDSP1NT5EDEGS1 | |
| SCHEMBL11342692 | 0.86 | ENPP2 (0.50) | ENPP2CASP6CTDSP1DEGS1RAB9A | |
| SCHEMBL10909132 | 0.86 | ENPP2 (0.50) | ENPP2CASP6CTDSP1NT5EDEGS1 | |
| SCHEMBL11427784 | 0.85 | CASP6 (0.60) | ENPP2CASP6CTDSP1NT5EMAPT | |
| SCHEMBL11435442 | 0.84 | CASP6 (0.49) | ENPP2CASP6CTDSP1NT5ERAB9A | |
| SCHEMBL11204758 | 0.83 | CASP6 (0.62) | ENPP2CASP6CTDSP1NT5ERAB9A | |
| SCHEMBL11428137 | 0.83 | CASP6 (0.47) | ENPP2CASP6CTDSP1NT5ERAB9A | |
| SCHEMBL11425747 | 0.83 | MAPT (0.55) | ENPP2RAB9ANPC1MAPTTP53 | |
| SCHEMBL11440412 | 0.82 | ENPP2 (0.43) | ENPP2CASP6CTDSP1NT5ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |