Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429899 | 0.89 | ADRA1D (0.46) | SMN1; SMN2ADRA1DADRA1AADRA1BBCHE | |
| SCHEMBL11435585 | 0.87 | BCHE (0.53) | OPRM1OPRD1OPRK1BCHE | |
| SCHEMBL11436508 | 0.86 | ACACB (0.40) | ACACBNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL11435607 | 0.83 | HPGD (0.45) | NPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL11437547 | 0.83 | ACACB (0.44) | ACACBOPRM1OPRD1OPRK1NPC1 | |
| SCHEMBL11429459 | 0.83 | OPRM1 (0.51) | OPRM1OPRD1OPRK1ADRA1AKCNH2 | |
| SCHEMBL11441561 | 0.80 | KDM4E (0.46) | SMN1; SMN2ADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL11442329 | 0.77 | MAPT (0.40) | ACACBNPC1MAPTRAB9AMAPK1 | |
| SCHEMBL11430227 | 0.75 | HPGD (0.44) | ACACBNPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL11429863 | 0.74 | MAPT (0.49) | ACACBNPC1MAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017376-A1 | Phenylacetamide compounds and an analgesic composition containing them | KISSEI PHARMACEUTICAL CO. LTD (JP) | 1980-10-15 | — | — | EP | disclosed |