Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429899 | 0.91 | ADRA1D (0.46) | KDM4EADRA1DADRA1AADRA1BSMPD1 | |
| SCHEMBL11437547 | 0.88 | ACACB (0.44) | GAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11434849 | 0.84 | OPRM1 (0.54) | DRD2DRD3 | |
| SCHEMBL11429882 | 0.83 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BSMPD1GAA | |
| SCHEMBL11435253 | 0.83 | KMT2A (0.48) | ADRA1DADRA1AADRA1BGAASMN1; SMN2 | |
| SCHEMBL11435182 | 0.80 | ACACB (0.39) | KDM4EADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL11436980 | 0.77 | DRD2 (0.51) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL11442594 | 0.77 | SMN1; SMN2 (0.44) | KDM4EGAAHTTSMN1; SMN2MEN1 | |
| SCHEMBL11435585 | 0.75 | BCHE (0.53) | MEN1KMT2A | |
| SCHEMBL1966331 | 0.75 | ADRA1D (0.67) | KDM4EADRA1DADRA1AADRA1BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017376-A1 | Phenylacetamide compounds and an analgesic composition containing them | KISSEI PHARMACEUTICAL CO. LTD (JP) | 1980-10-15 | — | — | EP | disclosed |