Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435518 | 0.90 | LMNA (0.35) | CES2LMNAHSD17B10 | |
| SCHEMBL8961229 | 0.80 | LMNA (0.40) | CES2LMNAZDHHC7ALDH1A1 | |
| SCHEMBL11496943 | 0.78 | CES2 (0.41) | CES2CYP3A4TSHRHPGDSMN1; SMN2 | |
| SCHEMBL7168676 | 0.78 | CES2 (0.44) | CES2LMNAZDHHC7 | |
| SCHEMBL8961419 | 0.75 | LMNA (0.46) | CES2TSHRLMNAZDHHC7ALDH1A1 | |
| SCHEMBL22525823 | 0.71 | CES2 (0.50) | CES2CYP3A4TSHRHPGDSMN1; SMN2 | |
| SCHEMBL11711197 | 0.69 | FDPS (0.40) | CYP3A4TSHRLMNAZDHHC7PLA2G2A | |
| SCHEMBL28581750 | 0.68 | CES2 (0.52) | CES2CYP3A4TSHRHPGDSMN1; SMN2 | |
| SCHEMBL21106219 | 0.68 | CES2 (0.47) | CES2CYP3A4TSHRHPGDMAPT | |
| SCHEMBL26406112 | 0.68 | CES2 (0.47) | CES2CYP3A4TSHRHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198430-A | ANTIULCER AND ANTIASTHMATIC AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1980-04-15 | — | — | US | disclosed |