Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961229 | 0.89 | LMNA (0.40) | LMNAALDH1A1CES2CES1ZDHHC7 | |
| SCHEMBL7168676 | 0.87 | CES2 (0.44) | LMNACES2CES1ZDHHC7 | |
| SCHEMBL8961214 | 0.83 | LMNA (0.37) | LMNACYP2C19 | |
| SCHEMBL11435518 | 0.78 | LMNA (0.35) | LMNACES2 | |
| SCHEMBL11435477 | 0.75 | CES2 (0.40) | LMNAALDH1A1CES2ZDHHC7TSHR | |
| SCHEMBL8961408 | 0.72 | LMNA (0.38) | LMNAALDH1A1CYP2C19 | |
| SCHEMBL6101319 | 0.70 | SMN1; SMN2 (0.37) | LMNACYP2C19ZDHHC7 | |
| SCHEMBL9770211 | 0.70 | LMNA (0.37) | LMNACYP2C19 | |
| SCHEMBL11711197 | 0.69 | FDPS (0.40) | LMNAZDHHC7TSHR | |
| SCHEMBL11718680 | 0.68 | CES2 (0.44) | LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532402-A | Process for producing optically active hydroxyalkylphosphonates | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-07-02 | — | — | US | disclosed |