Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11784878 | 0.89 | PDE4D (0.73) | L3MBTL1ALDH1A1LMNAPDE10AKDM4E | |
| SCHEMBL4393433 | 0.89 | ALDH1A1 (0.68) | L3MBTL1ALDH1A1LMNAPDE10AKDM4E | |
| SCHEMBL11435535 | 0.87 | ALDH1A1 (0.74) | L3MBTL1ALDH1A1LMNAPDE10AKDM4E | |
| SCHEMBL14305182 | 0.85 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1LMNAPDE10AKDM4E | |
| SCHEMBL9604076 | 0.84 | PIK3CD (0.76) | L3MBTL1ALDH1A1LMNAPDE10AKDM4E | |
| Methaqualone SCHEMBL29386732 | 0.83 | ALDH1A1 (1.00) | L3MBTL1ALDH1A1LMNAMAPTPDE7A | |
| Methaqualone SCHEMBL20471677 | 0.83 | ALDH1A1 (1.00) | L3MBTL1ALDH1A1LMNAMAPTPDE7A | |
| Methaqualone SCHEMBL29355239 | 0.83 | ALDH1A1 (1.00) | L3MBTL1ALDH1A1LMNAMAPTPDE7A | |
| Methaqualone SCHEMBL43892 | 0.83 | ALDH1A1 (1.00) | L3MBTL1ALDH1A1LMNAMAPTPDE7A | |
| SCHEMBL8242227 | 0.83 | NPC1 (0.70) | L3MBTL1ALDH1A1LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183931-A | SEDATIVE-HYPNOTICS, ANTICONVULSANTS, CENTRAL NERVOUS SYSTEM DEPRESSANTS | RESEARCH CORPORATION (US) | 1980-01-15 | — | — | US | disclosed |