Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432958 | 0.95 | ACE (0.41) | ACE | |
| SCHEMBL6389769 | 0.95 | ACE (0.41) | ACE | |
| SCHEMBL28780658 | 0.79 | EPHX2 (0.39) | — | |
| SCHEMBL14080195 | 0.77 | DPP4 (0.40) | ACE | |
| SCHEMBL27581728 | 0.76 | L3MBTL1 (0.53) | — | |
| SCHEMBL11434077 | 0.76 | POLB (0.55) | — | |
| SCHEMBL7377396 | 0.76 | ACE (0.62) | ACE | |
| SCHEMBL2983461 | 0.76 | POLB (0.35) | ACE | |
| SCHEMBL3515949 | 0.76 | POLB (0.35) | ACE | |
| SCHEMBL3517261 | 0.76 | POLB (0.35) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4206122-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1980-06-03 | — | — | US | disclosed |